I have a .45 acp with a 10" barrel (sbr) that is one of the my guns that is at the top of the fun list. My impression that the only thing that might make it more better would be a suppressor. On my to do list is a .458 with a similar length barrel. I think it would be more akin to a catapult impact when it hit something at 100 yds or so with a 400gn bullet.
Around here, the BO is referred to as that rainbow gun due to the trajectory. Everyone agrees that it is a nice suppressed round but no one seems to know what to do with it and no one talks about it anymore.
I don't hear much at all about the .224V or any of the recently introduced calibers either. Of course, we are out in the boondocks and most guys that actually shoot a lot tend to stick to stuff that is tried and proven. It's hard to get deader than dead and things like .223/5.56, 22-250, and .308 work. Amazing how many guys I know pay absolutely no attention to bulletin board commandos. Idiots like me that have more guns than sense give them something to laugh about but they are right. They usually kill more things with two or three guns that some of us will ever shoot with 40 or so.
It should scare manufacturers to know that much of the market is either built upon fear, or a few of us nuts that like them a lot more than we use them. It's a house of cards with all the calibers that are being "invented" and then forgotten when they don't take off with other than initial interest.