IMHO, the grooves are not as big of a deal as the Chamber. Now, when you combine everything, they all add up and will make a difference in pressure.
So if you have a 1:11"/6-Groove/SPCII Chamber and a 1:11"/4-Groove/SPCII Chamber, the difference in pressure really aren't tha much, but if you have a 1:10"/6-Groove/SPCII and a 1:12"/3-Groove/SPCII Chamber, then you will have a great decrease in pressure. Remember, the 1:10"/6-Groove/SPCII is the MINIMUM specs for a "C" rating. Anything better than that is just gravy.
So if you have a 1:11"/6-Groove/SPCII Chamber and a 1:11"/4-Groove/SPCII Chamber, the difference in pressure really aren't tha much, but if you have a 1:10"/6-Groove/SPCII and a 1:12"/3-Groove/SPCII Chamber, then you will have a great decrease in pressure. Remember, the 1:10"/6-Groove/SPCII is the MINIMUM specs for a "C" rating. Anything better than that is just gravy.