AS,
I have shot a lot of animals with the TSX, and I think it is too tough, in general, for light-skinned game. If you hit bone then you are OK, but if you just shoot them through the ribs / thorax / lungs, the bullet doesn't transfer as much energy as would a soft point.
I agree with Tim that the SPH or Accubond is going to be the best deer bullet.
However, that said, I haven't seen anything ....not anything... that performs like the Barnes Tipped-TSX. If you are inclined to spend a little more $$ on bullets, the TTSX is the one you want. If you don't, then if hunting deer, use the Accubond.